Stress induced T wave normalization: a new marker of myocardial ischaemia

Is Hsp27 a marker of myocardial ischaemia?

BACKGROUND Heat shock protein (Hsp) 27 expression in cardiomyocytes increases in response to ischaemia. The extracellular release of Hsp27 from cardiomyocytes is proportional to its intracellular levels. AIM To assess the influence of significant coronary artery disease (CAD), which by definition results in chronic myocardial ischaemia, on blood serum levels of Hsp27. METHODS Blood serum le...

The Significance of T-wave Pseudo-normalization in Myocardial I

Systematic review of mental stress-induced myocardial ischaemia.

There is growing evidence that psychosocial stress can influence the natural history of coronary heart disease. Epidemiological studies indicate that psychosocial factors both contribute to the development of coronary artery disease (CAD), and increase risk of cardiac dysfunction and the likelihood of cardiac events in susceptible patients with established disease. An important method of assess...

Exercise-induced T-wave normalization predicts recovery of regional contractile function after anterior myocardial infarction.

AIMS We investigated the ability of T-wave pseudonormalization and ST-segment elevation, which are demonstrated in infarct-related leads during submaximal exercise testing, to predict late recovery of contractile function. METHODS We studied 88 consecutive patients (73 males, mean age 59 +/- 8 years) with anterior infarction, persistent T-wave inversion and a documented lesion of the proximal...

Evaluation of ischaemia-modified albumin as a marker of myocardial ischaemia in end-stage renal disease.

The early diagnosis of myocardial ischaemia is problematic in patients with ESRD (end-stage renal disease). The aim of the present study was to determine whether IMA (ischaemia-modified albumin) increases during dobutamine stress and detects myocardial ischaemia in patients with ESRD. A total of 114 renal transplant candidates were studied prospectively, and all received DSE (dobutamine stress ...